RIG-I Goes Beyond Naked Recognition

被引：8

作者：

Bowzard, J. Bradford ^{[1
]}

Ranjan, Priya ^{[1
]}

Sambhara, Suryaprakash ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Immunol & Pathogenesis Branch, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30329 USA

来源：

CELL HOST & MICROBE | 2013年 / 13卷 / 03期

关键词：

RNA;

D O I：

10.1016/j.chom.2013.02.012

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

It is currently unclear at which point during viral replication that RNA genomes are first recognized as nonself by the immune system. In this issue of Cell Host & Microbe, Weber et al. show that incoming nucleocapsid-bound genomes are sufficient to bind and activate innate immune sensors.

引用

页码：247 / 249

页数：4

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