Protocol for the successful treatment of venous ulcers

被引:45
作者
Brem, H
Kirsner, RS
Falanga, V
机构
[1] Columbia Univ, Coll Phys & Surg, Dept Surg, New York, NY 10034 USA
[2] Miami Univ, Sch Med, Vet Adm Med Ctr, Dept Dermatol & Cutaneous Surg, Miami, FL USA
[3] Boston Univ, Sch Med, Dept Dermatol, Boston, MA USA
[4] Boston Univ, Sch Med, Dept Biochem, Boston, MA USA
关键词
D O I
10.1016/S0002-9610(03_00284-8
中图分类号
R61 [外科手术学];
学科分类号
摘要
Venous ulcers affect up to 2.5 million patients per year in the United States. Although not usually fatal, these chronic wounds severely affect patients' quality of life because of impaired mobility and substantial loss of productivity. Although venous ulcers are typically small initially, they are often undertreated, progressing to larger ulcers that are associated with more serious complications requiring more complex treatments. In this report we detail the pathogenesis of venous ulcers together with potential complications, including exudate, erythema, cellulitis, dermatitis, pain, and possible malignancy. The clinician's regimen should always include a wide range of treatment modalities to ensure comprehensive care and effective wound closure. The treatment modalities and specific protocol for venous ulcers are discussed, and include topical dressings, antibiotics, debridement, compression therapy, and cellular therapy. These treatment modalities, in combination with early recognition and regular monitoring using digital photography and planimetry measurements, will ensure rapid healing and minimize complications and cost. (C) 2004 Excerpta Medica, Inc. All rights reserved.
引用
收藏
页码:1S / 8S
页数:8
相关论文
共 53 条
[1]
REAL-TIME ULTRASOUND DIAGNOSIS OF DEEP-VEIN THROMBOSIS - A COMPARISON WITH VENOGRAPHY [J].
AITKEN, AGF ;
GODDEN, DJ .
CLINICAL RADIOLOGY, 1987, 38 (03) :309-313
[2]
VENOUS LEG ULCERS AND SQUAMOUS-CELL CARCINOMA - A LARGE-SCALE EPIDEMIOLOGIC-STUDY [J].
BALDURSSON, B ;
SIGURGEIRSSON, B ;
LINDELOF, B .
BRITISH JOURNAL OF DERMATOLOGY, 1995, 133 (04) :571-574
[3]
Human papillomavirus in venous ulcers with and without squamous cell carcinoma [J].
Baldursson, BT ;
Beitner, H ;
Syrjänen, S .
ARCHIVES OF DERMATOLOGICAL RESEARCH, 2000, 292 (06) :275-278
[4]
Therapeutic approach to chronic venous insufficiency and its complications:: Place of Daflon® 500 mg [J].
Bergan, JJ ;
Schmid-Schönbein, GW ;
Takase, S .
ANGIOLOGY, 2001, 52 :S43-S47
[5]
MALIGNANT FIBROUS HISTIOCYTOMA - A NEW COMPLICATION OF CHRONIC VENOUS ULCERATION [J].
BERTHJONES, J ;
GRAHAMBROWN, RAC ;
FLETCHER, A ;
HENDERSON, HP ;
BARRIE, WW .
BRITISH MEDICAL JOURNAL, 1989, 298 (6668) :230-231
[6]
Healing of venous ulcers of long duration with a bilayered living skin substitute: Results from a general surgery and dermatology department [J].
Brem, H ;
Balledux, J ;
Sukkarieh, T ;
Carson, P ;
Falanga, V .
DERMATOLOGIC SURGERY, 2001, 27 (11) :915-919
[7]
Brem Harold, 2003, Surg Technol Int, V11, P161
[8]
PERICAPILLARY FIBRIN IN THE ULCER-BEARING SKIN OF THE LEG - THE CAUSE OF LIPODERMATOSCLEROSIS AND VENOUS ULCERATION [J].
BURNAND, KG ;
WHIMSTER, I ;
NAIDOO, A ;
BROWSE, NL .
BMJ-BRITISH MEDICAL JOURNAL, 1982, 285 (6348) :1071-1072
[9]
MICROCIRCULATORY ASPECTS OF VENOUS ULCERATION [J].
BUTLER, CM ;
SMITH, PDC .
JOURNAL OF DERMATOLOGIC SURGERY AND ONCOLOGY, 1994, 20 (07) :474-480
[10]
Bilayered bioengineered skin substitute (Apligraf®) -: A review of its use in the treatment of venous leg ulcers and diabetic foot ulcers [J].
Curran, MP ;
Plosker, GL .
BIODRUGS, 2002, 16 (06) :439-455