Synthesis of new chiral imidazolium salts derived from amino acids: their evaluation in chiral molecular recognition

被引：38

作者：

Altava, Belen ^{[1
]}

Barbosa, Dalgi S. ^{[1
]}

Isabel Burguete, M. ^{[1
]}

Escorihuela, Jorge ^{[1
]}

Luis, Santiago V. ^{[1
]}

机构：

[1] Univ Jaume 1, Dept Quim Inorgan & Organ, Castellon de La Plana 12071, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2009年 / 20卷 / 09期

关键词：

IONIC LIQUIDS; CHROMATOGRAPHIC SEPARATION; NMR ENANTIODISCRIMINATION; CARBOXYLIC-ACIDS; SOLVATING AGENTS; SHIFT-REAGENT; DESIGN; OPTIMIZATION; RECEPTORS; VERSATILE;

D O I：

10.1016/j.tetasy.2009.03.028

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A family of new imidazolium salts derived from natural amino acids has been synthesized and tested for NMR enantiodiscrimination, as chiral shift reagents, of carboxylic acids. These imidazolium receptors contain different Structural modifications and the splitting of the signals of the acids, after addition of the corresponding CSRs, depends on these structural variables. Compound 8b exhibited the strongest chiral solvating properties for racemic Mosher acid and was recognized as a suitable CSR for the determination of its enantiomeric composition. (c) 2009 Elsevier Ltd. All rights reserved.

引用

页码：999 / 1003

页数：5

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