Potent, versatile, and stable: Thiazolyl thioglycosides as glycosyl donors

被引：109

作者：

Demchenko, AV ^{[1
]}

Pornsuriyasak, P ^{[1
]}

De Meo, C ^{[1
]}

Malysheva, NN ^{[1
]}

机构：

[1] Univ Missouri, Dept Chem & Biochem, St Louis, MO 63121 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 23期

关键词：

carbohydrates; chemoselectivity; glycosides; glycosylation;

D O I：

10.1002/anie.200454047

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Donating with a difference: Thiazolyl (Taz) substituted thioglycosides have been successfully used in the synthesis of both 1,2-trans- and 1,2-cis-glycosides and also have found application in convergent oligosaccharide synthesis. In addition, this study has demonstrated that STaz and SEt moieties are fully orthogonal (see scheme, Bn = benzyl; X = STaz, Y = SEt or X = SEt,Y = STaz).

引用

页码：3069 / 3072

页数：4

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