Mild method for the synthesis of amidines by the electrophilic activation of amides

被引：57

作者：

Charette, AB ^{[1
]}

Grenon, M ^{[1
]}

机构：

[1] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 11期

基金：

加拿大自然科学与工程研究理事会;

关键词：

amides; amidines;

D O I：

10.1016/S0040-4039(00)00040-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of amidines was achieved by the addition of amines to amides that were previously activated with trifluoromethanesulfonic anhydride (triflic anhydride) and pyridine. Various disubstituted and trisubstituted amidines were prepared in yields up to 84%. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：1677 / 1680

页数：4

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