Dengue Virus- and Hepatitis C Virus- Induced Replication and Assembly Compartments: the Enemy Inside-Caught in the Web

被引：110

作者：

Chatel-Chaix, Laurent ^{[1
]}

Bartenschlager, Ralf ^{[1
]}

机构：

[1] Heidelberg Univ, Dept Infect Dis, Heidelberg, Germany

来源：

JOURNAL OF VIROLOGY | 2014年 / 88卷 / 11期

关键词：

3-DIMENSIONAL ARCHITECTURE; MEMBRANE-ALTERATIONS; LIPID DROPLET; LOW-DENSITY; PROTEIN; SITES;

D O I：

10.1128/JVI.03404-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Dengue virus (DENV) and hepatitis C virus (HCV), members of the family Flaviviridae, are global human health concerns. As positive-strand RNA viruses, they each replicate in the cytoplasm of infected cells and induce distinct membranous replication compartments where most, if not all, steps of the viral life cycle occur. This Gem briefly reviews the most recent insights into the architecture and functional properties of membranous replication and assembly sites induced by DENV and HCV.

引用

页码：5907 / 5911

页数：5

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