Pentafluorophenyltrifluorosilane in the silicon Mannich reaction

被引：13

作者：

Dilman, Alexander D. ^{[1
]}

Gorokhov, Vladimir V. ^{[1
]}

Belyakov, Pavel A. ^{[1
]}

Struchkova, Marina I. ^{[1
]}

Tartakovsky, Vladimir A. ^{[1
]}

机构：

[1] ND Zelinskii Inst Organ Chem, Moscow 119991, Russia

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 35期

关键词：

fluorinated silanes; hypervalent silicon; Mannich reaction;

D O I：

10.1016/j.tetlet.2006.06.164

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of alpha-C6F5-substituted amines by a three-component coupling reaction of C6F5SiF3, aromatic aldehydes, and N-trimethylsilylamines has been elaborated. The optimized conditions include performing the reaction in dimethylformamide in the presence of stoichiometric amounts of lithium acetate. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：6217 / 6219

页数：3

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