Acylated flavonol glycosides from the flower of Inula britannica

被引：60

作者：

Park, EJ ^{[1
]}

Kim, Y ^{[1
]}

Kim, J ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 01期

关键词：

D O I：

10.1021/np990271r

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new acylated flavonol glycosides, patuletin 7-O-(6"-isobutyryl)glucoside (1), patuletin 7-O-[6"-(2-methylbutyryl)]glucoside (2), and patuletin 7-O-(6"-isovaleryl)glucoside (3), were isolated from the n-BuOH extract of Inula britannica flowers by bioassay-guided fractionation, together with other known flavonoids. The structures were elucidated by 1D and 2D NMR, FABMS, and other spectral analyses. The eight flavonoids, including new compounds (1-3), patulitrin (7), nepitrin (8), axillarin (10), patuletin (11), and luteolin (12), showed profound antioxidant activity in DPPH assay and cytochrome-c reduction assay using HL-60 cell culture system.

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页码：34 / 36

页数：3

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