Advancing glycomics: Implementation strategies at the consortium for functional glycomics

被引:153
作者
Raman, R [1 ]
Venkataraman, M [1 ]
Ramakrishnan, S [1 ]
Lang, W [1 ]
Raguram, S [1 ]
Sasisekharan, R [1 ]
机构
[1] MIT, Harvard MIT Div Hlth Sci & Technol, Ctr Environm Hlth Sci, Ctr Biomed Engn,Biol Engn Div, Cambridge, MA 02139 USA
关键词
bioinformatics; CFG; glycan; glycomics;
D O I
10.1093/glycob/cwj080
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Glycomics-an integrated approach to study structure-function relationships of complex carbohydrates (or glycans)-is an emerging field in this age of post-genomics. Realizing the importance of glycomics, many large scale research initiatives have been established to generate novel resources and technologies to advance glycomics. These initiatives are generating and cataloging diverse data sets necessitating the development of bioinformatic platforms to acquire, integrate, and disseminate these data sets in a meaningful fashion. With the consortium for functional glycomics (CFG) as the model system, this review discusses databases and the bioinformatics platform developed by this consortium to advance glycomics.
引用
收藏
页码:82R / 90R
页数:9
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