At the center of eukaryotic life

被引:167
作者
Moss, T
Stefanovsky, VY
机构
[1] Univ Laval, Ctr Rech Hotel Dieu Quebec, Ctr Canc Res, Quebec City, PQ G1R 2J6, Canada
[2] Univ Laval, Ctr Rech Hotel Dieu Quebec, Dept Med Biol, Quebec City, PQ G1R 2J6, Canada
关键词
D O I
10.1016/S0092-8674(02)00761-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The ribosomal RNA genes encode the enzymatic scaffold of the ribosome and thereby perform perhaps the most basic of all housekeeping functions. However, recent data suggests that they might also control important aspects of cell behavior.
引用
收藏
页码:545 / 548
页数:4
相关论文
共 19 条
  • [1] In vivo binding and hierarchy of assembly of the yeast RNA polymerase I transcription factors
    Bordi, L
    Cioci, F
    Camilloni, G
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (03) : 753 - 760
  • [2] BOUKHGALTER B, 2002, IN PRESS GENE
  • [3] Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I
    Fath, S
    Milkereit, P
    Peyroche, G
    Riva, M
    Carles, C
    Tschochner, H
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (25) : 14334 - 14339
  • [4] Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1
    Hannan, KM
    Hannan, RD
    Smith, SD
    Jefferson, LS
    Lun, MY
    Rothblum, LI
    [J]. ONCOGENE, 2000, 19 (43) : 4988 - 4999
  • [5] The role of acetylation in rDNA transcription
    Hirschler-Laszkiewicz, I
    Cavanaugh, A
    Hu, QY
    Catania, J
    Avantaggiati, ML
    Rothblum, LI
    [J]. NUCLEIC ACIDS RESEARCH, 2001, 29 (20) : 4114 - 4124
  • [6] TFIIH plays an essential role in RNA polymerase I transcription
    Iben, S
    Tschochner, H
    Bier, M
    Hoogstraten, D
    Hozák, P
    Egly, JM
    Grummt, I
    [J]. CELL, 2002, 109 (03) : 297 - 306
  • [7] The interferon-inducible nucleolar p204 protein binds the ribosomal RNA-specific UBF1 transcription factor and inhibits ribosomal RNA transcription
    Liu, CJ
    Wang, H
    Lengyel, P
    [J]. EMBO JOURNAL, 1999, 18 (10) : 2845 - 2854
  • [8] UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat
    O'Sullivan, AC
    Sullivan, GJ
    McStay, B
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (02) : 657 - 668
  • [9] The nucleolus: an old factory with unexpected capabilities
    Olson, MOJ
    Dundr, M
    Szebeni, A
    [J]. TRENDS IN CELL BIOLOGY, 2000, 10 (05) : 189 - 196
  • [10] A step subsequent to preinitiation complex assembly at the ribosomal RNA gene promoter is rate limiting for human RNA polymerase I-dependent transcription
    Panov, KI
    Friedrich, JK
    Zomerdijk, JCBM
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (08) : 2641 - 2649