Comparative chemical composition and antioxidant activities of wild and cultivated Laurus nobilis L. leaves and Foeniculum vulgare subsp piperitum (Ucria) coutinho seeds

被引:121
作者
Conforti, Filomena [1 ]
Statti, Giancarlo
Uzunov, Dimitar
Menichini, Francesco
机构
[1] Univ Calabria, Dept Pharmaceut Sci, I-87036 Cosenza, Italy
[2] Univ Calabria, Bot Gardens, I-87036 Cosenza, Italy
[3] Museum Nat Hist, I-87036 Cosenza, Italy
关键词
Laurus nobilis; Foeniculum vulgare subsp.piperition; radical scavenging; antioxidant activity; phenolic content;
D O I
10.1248/bpb.29.2056
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The chemical composition and antioxidant activities of wild and cultivated Laurus nobilis leaves and Foeniculum vulgare subsp. piperitum seeds were determined. Differences were found in the total phenolic content of fennel. GC-MS analysis of the non polar fractions showed a different composition between wild and cultivated plants. Cultivated laurel had a high content of terpenes such as linool, alpha-terpinol, alpha-terpinyl acetate, thymol, caryophyllene, aromandrene, selinene, farnesene, and cadinene, while wild laurel had a high content of eugenol and methyl eugenol, vitamin E, and sterols. The antioxidant potential of the extracts was determined using three complementary methods. Wild plants showed greater radical scavenging activity than the cultivated plants. The extracts also exhibited a significant antioxidant capacity also in the beta-carotene-linoleic acid test system. A high level of antioxidant activity was observed in wild laurel (IC50 = 1 mu g/ml). Significant antioxidant activity measured in bovine brain was observed in wild laurel.
引用
收藏
页码:2056 / 2064
页数:9
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