Multicenter patient self-reporting questionnaire on impotence, incontinence and stricture after radical prostatectomy

被引:151
作者
Kao, TC
Cruess, DF
Garner, D
Foley, J
Seay, T
Friedrichs, P
Thrasher, JB
Mooneyhan, RD
McLeod, DG
Moul, JW
机构
[1] Uniformed Serv Univ Hlth Sci, Dept Prevent Med, Bethesda, MD USA
[2] Uniformed Serv Univ Hlth Sci, Dept Biometr, Div Epidemiol & Biostat, Bethesda, MD USA
[3] Uniformed Serv Univ Hlth Sci, Ctr Prostate Dis Res, Dept Surg, Bethesda, MD USA
[4] Natl Naval Med Ctr, Dept Radiat Oncol, Bethesda, MD USA
[5] Malcolm Grow Med Ctr, Dept Urol, Andrews Air Forces Base, MD USA
[6] Brooke Army Med Ctr, Dept Urol, Ft Sam Houston, TX 78234 USA
[7] Wilford Hall USAF Med Ctr, Lackland AFB, TX 78236 USA
[8] Univ Kansas, Sch Med, Kansas City, KS USA
[9] Walter Reed Army Med Ctr, Serv Urol, Dept Surg, Washington, DC 20307 USA
[10] Walter Reed Army Med Ctr, Serv Urol, Dept Clin Invest, Washington, DC 20307 USA
关键词
prostate; prostatectomy; prostatic neoplasms; quality of life; epidemiology;
D O I
10.1016/S0022-5347(05)67819-6
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: We determined the incidence of patient self-reported post-prostatectomy incontinence, impotence, bladder neck contracture and/or urethral stricture, sexual function satisfaction, quality of life and willingness to undergo treatment again in a large multicenter group of men who underwent radical prostatectomy. We also determined whether the morbidities of sexual function satisfaction, quality of life and bladder neck contracture and/or urethral stricture are predictable from demographic and postoperative prostate cancer factors. Materials and Methods: A self-reporting questionnaire was completed and returned by 1,069 of 1,396 eligible patients (77%) who underwent radical prostatectomy between 1962 and 1997. Of the respondents 868 (85.7%) underwent surgery after 1990 and in all prostatectomy had been done a minimum of 6 months previously. Questionnaire results were independently analyzed by a third party for morbidity tabulation and the association of patient reported satisfaction. Results: The patient self-reported incidence of any degree of post-prostatectomy incontinence, impotence and bladder neck contracture or urethral stricture was 65.6%, 88.4% and 20.5%, respectively, The incidence of incontinence requiring protection was 33% and only 2.8% of respondents had persistent bladder neck contracture or urethral stricture. Although incontinence and impotence significantly affected self-reported sexual function satisfaction, quality of life and willingness to undergo treatment again (p = 0.001), 77.5% of patients would elect surgery again. This finding remained true even after adjusting for demographic variables, and the time between surgery and the survey by multiple logistic regression. Conclusions: Although radical prostatectomy morbidity is common and affects self-reported overall quality of life, most patients would elect the same treatment again. Impotence and post-prostatectomy incontinence were significantly associated with sexual function satisfaction, quality of life and willingness to undergo treatment again. Bladder neck contracture and/or urethral stricture was associated with willingness to undergo treatment again after adjusting for demographic variables and time from surgery to the survey.
引用
收藏
页码:858 / 864
页数:7
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