Nucleotide sequence of a Drosophila melanogaster cDNA encoding a calnexin homologue

被引：17

作者：

Christodoulou, S

Lockyer, AE

Foster, JM

Hoheisel, JD

Roberts, DB

机构：

[1] UNIV OXFORD,DEPT BIOCHEM,GENET LAB,OXFORD OX1 3QU,ENGLAND

[2] UNIV ABERDEEN,DEPT ZOOL,ABERDEEN AB9 2TN,SCOTLAND

[3] UNIV OXFORD,JOHN RADCLIFFE HOSP,INST MOL MED,MOL PARASITOL GRP,OXFORD OX3 9DU,ENGLAND

[4] DEUTSCH KREBSFORSCHUNGSZENTRUM,IMMUNOCHEM ABT,D-69120 HEIDELBERG,GERMANY

来源：

GENE | 1997年 / 191卷 / 02期

基金：

英国惠康基金;

关键词：

chaperone; endoplasmic reticulum; calcium binding; glycosylation;

D O I：

10.1016/S0378-1119(97)00025-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A cDNA which encodes a calnexin (Cnx)-like protein from Drosophila melanogaster has been characterized. The deduced amino acid sequence shares several regions of homology with Cnx from other sources with two conserved motifs each repeated four times. The gene was found to be transcribed in various tissues and at all developmental stages. We have mapped the gene at chromosomal position 99A and we have also mapped the related gene coding for Drosophila calreticulin at 85E. (C) 1997 Elsevier Science B.V.

引用

页码：143 / 148

页数：6

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