Are there proliferating neuronal precursors in adult rat dorsal root ganglia?

被引：33

作者：

Ciaroni, S ^{[1
]}

Cecchini, T

Cuppini, R

Ferri, P

Ambrogini, P

Bruno, C

Del Grande, P

机构：

[1] Univ Urbino, Inst Morphol Sci, I-61029 Urbino, Italy

[2] Univ Urbino, Inst Physiol Sci, I-61029 Urbino, Italy

来源：

NEUROSCIENCE LETTERS | 2000年 / 281卷 / 01期

关键词：

postnatal neurogenesis; dorsal root ganglia; proliferation; differentiation; tocopherols; 5-bromo-2-deoxyuridine;

D O I：

10.1016/S0304-3940(00)00785-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The origin of new neurons in dorsal root ganglia of adult rat was investigated using an experimental model in which postnatal neurogenesis naturally occurring is enhanced and restricted in a brief period of life. Possible mitotic origin of new neurons was investigated by means of 5-bromo-2-deoxyuridine, anti-NF 200 antibody was used to detect if proliferated cells showed a neuronal phenotype. The results suggest that postnatal neurogenesis in dorsal root ganglia could depend only in part on precursor proliferation and that normally new neurons derive from the late differentiation of postmitotic cells. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：69 / 71

页数：3

共 14 条

[1] MATURATION OF THE SPONTANEOUS TRANSMITTER RELEASE BY REGENERATED NERVE-ENDINGS IN VITAMIN-E-DEFICIENT RATS [J].