Telorneres: Not all breaks are equal

被引：9

作者：

Purdy, A ^{[1
]}

Su, TT ^{[1
]}

机构：

[1] Univ Colorado, Boulder, CO 80309 USA

来源：

CURRENT BIOLOGY | 2004年 / 14卷 / 15期

关键词：

D O I：

10.1016/j.cub.2004.07.042

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ATM, Rad50 and Mre11 have been shown to prevent telomere fusion in Drosophila, thereby extending the protective role of DNA damage checkpoint proteins to non-canonical telomeres formed without telomerase. How do these proteins help chromosomal termini escape fusion through 'repair' while promoting repair of induced DNA breaks?

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页码：R613 / R614

页数：2

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