Study of an outbreak of cefoxitin-resistant Klebsiella pneumoniae in a general hospital

被引：24

作者：

Gazouli, M

Kaufmann, ME

Tzelepi, E

Dimopoulou, H

Paniara, O

Tzouvelekis, LS

机构：

[1] HELLENIC PASTEUR INST,DEPT BACTERIOL,ATHENS 11521,GREECE

[2] EVAGELISMOS GEN HOSP,MICROBIOL LAB,ATHENS 11521,GREECE

[3] CENT PUBL HLTH LAB,LAB HOSP INFECT,LONDON NW9 5HT,ENGLAND

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1997年 / 35卷 / 02期

关键词：

D O I：

10.1128/JCM.35.2.508-510.1997

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

During a 3-month period, six Klebsiella pneumoniae isolates resistant to cefoxitin and penicillin-inhibitor combinations were derived from patients in the intensive care unit of a hospital in Athens, Greece. Enterobacterial repetitive intergenic consensus PCR and pulsed-field gel electrophoresis provided evidence of the clonal origin of the isolates. Conventional techniques and ribotyping were inadequate in proving that the isolates were related. Resistance was due to a plasmidic class C beta-lactamase.

引用

收藏

页码：508 / 510

页数：3

相关论文

共 16 条

[1] Characterization of the plasmidic beta-lactamase CMY-2, which is responsible for cephamycin resistance [J].

Bauernfeind, A ;

Stemplinger, I ;

Jungwirth, R ;

Giamarellou, H .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (01) :221-224

[2] MOLECULAR EPIDEMIOLOGY OF PLASMID SPREAD AMONG EXTENDED BROAD-SPECTRUM BETA-LACTAMASE-PRODUCING KLEBSIELLA-PNEUMONIAE ISOLATES IN A PEDIATRIC HOSPITAL [J].

BINGEN, EH ;

DESJARDINS, P ;

ARLET, G ;

BOURGEOIS, F ;

MARIANIKURKDJIAN, P ;

LAMBERTZECHOVSKY, NY ;

DENAMUR, E ;

PHILIPPON, A ;

ELION, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (02) :179-184

[3] EMERGENCE OF RESISTANCE TO IMIPENEM IN ENTEROBACTER ISOLATES MASQUERADING AS KLEBSIELLA-PNEUMONIAE DURING THERAPY WITH IMIPENEM-CILASTATIN [J].

EHRHARDT, AF ;

SANDERS, CC ;

THOMSON, KS ;

WATANAKUNAKORN, C ;

TRUJILLANOMARTIN, I .

CLINICAL INFECTIOUS DISEASES, 1993, 17 (01) :120-122

[4] COMPARISON OF RIBOTYPING WITH CONVENTIONAL METHODS FOR THE TYPE IDENTIFICATION OF ENTEROBACTER-CLOACAE [J].

GARAIZAR, J ;

KAUFMANN, ME ;

PITT, TL .

JOURNAL OF CLINICAL MICROBIOLOGY, 1991, 29 (07) :1303-1307

[5] Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group 1 beta-lactamase (LAT-2) [J].

Gazouli, M ;

Tzouvelekis, LS ;

Prinarakis, E ;

Miriagou, V ;

Tzelepi, E .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (07) :1736-1740

[6] EPIDEMIOLOGIC-STUDY BY PULSED-FIELD GEL-ELECTROPHORESIS OF AN OUTBREAK OF EXTENDED-SPECTRUM BETA-LACTAMASE-PRODUCING KLEBSIELLA-PNEUMONIAE IN A GERIATRIC HOSPITAL [J].

GOUBY, A ;

NEUWIRTH, C ;

BOURG, G ;

BOUZIGES, N ;

CARLESNURIT, MJ ;

DESPAUX, E ;

RAMUZ, M .

JOURNAL OF CLINICAL MICROBIOLOGY, 1994, 32 (02) :301-305

[7] ERIC SEQUENCES - A NOVEL FAMILY OF REPETITIVE ELEMENTS IN THE GENOMES OF ESCHERICHIA-COLI, SALMONELLA-TYPHIMURIUM AND OTHER ENTEROBACTERIA [J].

HULTON, CSJ ;

HIGGINS, CF ;

SHARP, PM .

MOLECULAR MICROBIOLOGY, 1991, 5 (04) :825-834

[8] KLEBSIELLA-PNEUMONIAE INFECTIONS IN GREEK HOSPITALS - DISSEMINATION OF PLASMIDS ENCODING AN SHV-5 TYPE BETA-LACTAMASE [J].

LEGAKIS, NJ ;

TZOUVELEKIS, LS ;

HATZOUDIS, G ;

TZELEPI, E ;

GOURKOU, A ;

PITT, TL ;

VATOPOULOS, AC .

JOURNAL OF HOSPITAL INFECTION, 1995, 31 (03) :177-187

[9] ON THE INCIDENCE OF ANTIBIOTIC-RESISTANCE AMONG AEROBIC GRAM-NEGATIVE RODS ISOLATED IN GREEK HOSPITALS [J].

LEGAKIS, NJ ;

TZOUVELEKIS, LS ;

TSAKRIS, A ;

LEGAKIS, JN ;

VATOPOULOS, AC .

JOURNAL OF HOSPITAL INFECTION, 1993, 24 (03) :233-237

[10] MOLECULAR EPIDEMIOLOGY - APPLICATION OF CONTEMPORARY TECHNIQUES TO THE TYPING OF MICROORGANISMS [J].

MASLOW, JN ;

MULLIGAN, ME ;

ARBEIT, RD .

CLINICAL INFECTIOUS DISEASES, 1993, 17 (02) :153-164