Use of medications and polypharmacy are increasing among the elderly

被引:313
作者
Linjakumpu, T
Hartikainen, S
Klaukka, T
Veijola, J
Kivelä, SL
Isoaho, R
机构
[1] Univ Oulu, Dept Psychiat, FIN-90014 Oulu, Finland
[2] Harkatie Hlth Ctr, Lieto, Finland
[3] Univ Turku, Inst Clin Med, Gen Practice, Turku, Finland
[4] Social Insurance Inst, Ctr Res & Dev, Helsinki, Finland
[5] Municipal Hosp Kuopio, Kuopio, Finland
[6] Univ Kuopio, Dept Publ Hlth & Gen Practice, Div Geriatr, FIN-70211 Kuopio, Finland
关键词
aged; drug therapy; drug utilization; elderly; pharmacoepidemiology; polypharmacy;
D O I
10.1016/S0895-4356(02)00411-0
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
To assess changes in medicine use and polypharmacy, two cross-sectional surveys were carried out among community-dwelling persons aged 64 years or over in 1990-91 (n = 1, 13 1) and 1998-99 (n = 1, 197) in the municipality of Lieto in southwestern Finland. In addition to drug use, the questionnaire included items on social background, quality of life, and home nursing services. Among those surveyed, 78% in 1990-1991 and 88% in 1998-1999 (P = .001) used prescription drugs during 7 days prior to the interview. The most commonly used medications were for the cardiovascular and central nervous systems. The number of medications per person increased from 3.1 (SD 2.8) to 3.8 (SD 3.1) (P = .0001), and polypharmacy (concominant use of over five medications) increased from 19 to 25% (P = .006). These changes were most prominent among persons aged 85 years or over, especially among women. Polypharmacy is a complex and worrying phenomenon that merits more research. (C) 2002 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:809 / 817
页数:9
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