Terminal differentiation and left-handed Z-DNA: A review

被引：15

作者：

Gagna, CE

Kuo, HR

Lambert, WC

机构：

[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Pathol & Lab Med, Newark, NJ 07103 USA

[2] Fairleigh Dickinson Univ, Sch Nat Sci, Dept Biol, Teaneck, NJ 07666 USA

来源：

CELL BIOLOGY INTERNATIONAL | 1999年 / 23卷 / 01期

关键词：

Z-DNA; terminal differentiation; denaturation; single-stranded DNA;

D O I：

10.1006/cbir.1998.0327

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Nucleic acids control the expression of genes, and different conformations of DNA structure may regulate cell death. Left-handed Z-DNA, which is speculated to function as a transcriptional enhancer, may be directly influenced by the destructive effects;of terminal differentiation. The nicking-denaturation of double-stranded Z-DNA could possibly initiate and enhance terminal differentiation within specific tissues. (C) 1999 Academic Press.

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页码：1 / 5

页数：5

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