Highly efficient palladium-catalyzed boronic acid coupling reactions in water: Scope and limitations

被引：274

作者：

Badone, D

Baroni, M

Cardamone, R

Ielmini, A

Guzzi, U

机构：

[1] Research Center Sanofi-Midy, 38 20137 Milan, via Piranesi

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1997年 / 62卷 / 21期

关键词：

D O I：

10.1021/jo970439i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ''ligandless'' palladium acetate-catalyzed Suzuki cross-coupling reaction of ArX with aryl-and vinylboronic acids in water without organic cosolvent in the presence of tetrabutylammonium bromide is reported. Aryl bromides give high yields and considerably accelerate the coupling, A wide variety of functional groups can be tolerated. Aryl iodides, however, give. incomplete conversion and aryl triflate coupling shows no improvement over reported conditions.

引用

页码：7170 / 7173

页数：4

共 37 条

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