The International Human Epigenome Consortium Data Portal

被引：110

作者：

Bujold, David ^{[1
,2
]}

Morais, David Anderson de Lima ^{[3
]}

Gauthier, Carol ^{[3
]}

Cote, Catherine ^{[1
,2
]}

Caron, Maxime ^{[1
,2
]}

Kwan, Tony ^{[1
,2
]}

Chen, Kuang Chung ^{[4
]}

Laperle, Jonathan ^{[5
]}

Markovits, Alexei Nordell ^{[6
]}

Pastinen, Tomi ^{[1
,2
,7
]}

Caron, Bryan ^{[4
]}

Veilleux, Alain ^{[3
]}

Jacques, Pierre-Etienne ^{[3
,5
,6
,8
]}

Bourque, Guillaume ^{[1
,2
,7
]}

机构：

[1] McGill Univ, Montreal, PQ H3A 0G1, Canada

[2] Genome Quebec Innovat Ctr, Montreal, PQ H3A 0G1, Canada

[3] Univ Sherbrooke, Ctr Calcul Sci, Sherbrooke, PQ J1K 2R1, Canada

[4] McGill Univ, McGill High Performance Comp Ctr, Montreal, PQ H3C 1K3, Canada

[5] Univ Sherbrooke, Dept Informat, Sherbrooke, PQ J1K 2R1, Canada

[6] Univ Sherbrooke, Dept Biol, Sherbrooke, PQ J1K 2R1, Canada

[7] McGill Univ, Dept Human Genet, Montreal, PQ H3A 0G1, Canada

[8] CHU Sherbrooke, Ctr Rech, Sherbrooke, PQ J1H 5N4, Canada

来源：

CELL SYSTEMS | 2016年 / 3卷 / 05期

基金：

加拿大自然科学与工程研究理事会; 加拿大健康研究院;

关键词：

GENOME BROWSER; UCSC;

D O I：

10.1016/j.cels.2016.10.019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The International Human Epigenome Consortium (IHEC) coordinates the production of reference epigenome maps through the characterization of the regulome, methylome, and transcriptome from a wide range of tissues and cell types. To define conventions ensuring the compatibility of datasets and establish an infrastructure enabling data integration, analysis, and sharing, we developed the IHEC Data Portal (http://epigenomesportal.ca/ihec). The portal provides access to > 7,000 reference epigenomic datasets, generated from > 600 tissues, which have been contributed by seven international consortia: ENCODE, NIH Roadmap, CEEHRC, Blueprint, DEEP, AMED-CREST, and KNIH. The portal enhances the utility of these reference maps by facilitating the discovery, visualization, analysis, download, and sharing of epigenomics data. The IHEC Data Portal is the official source to navigate through IHEC datasets and represents a strategy for unifying the distributed data produced by international research consortia.

引用

页码：496 / +

页数：6

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