Synthesis of a C-linked antifreeze glycoprotein (AFGP) mimic: Probes for investigating the mechanism of action

被引：31

作者：

Ben, RN ^{[1
]}

Eniade, AA ^{[1
]}

Hauer, L ^{[1
]}

机构：

[1] SUNY Binghamton, Dept Chem, Binghamton, NY 13902 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 11期

关键词：

D O I：

10.1021/ol991025+

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A general convergent synthesis has been developed to afford a low molecular weight C-linked antifreeze glycoprotein (AFGP) mimic (9). Structural mimics of AFGPs have tremendous potential as probes to better understand how native AFGPs inhibit ice crystal growth in organisms that inhabit subzero environments.

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页码：1759 / 1762

页数：4

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