Brain repair by endogenous progenitors

被引:64
作者
Kruger, GM
Morrison, SJ [1 ]
机构
[1] Univ Michigan, Howard Hughes Med Inst, Dept Internal Med, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Howard Hughes Med Inst, Dept Cell & Dev Biol, Ann Arbor, MI 48109 USA
关键词
D O I
10.1016/S0092-8674(02)00899-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Stem cells within the adult brain can be stimulated by injury and growth factor treatment to replace damaged neurons, even neurons that are not normally generated in adults. Coupled with recent insights into the mechanism by which Nogo inhibits axonal regeneration, this discovery may inspire new treatments for central nervous system injuries and neurodegenerative diseases.
引用
收藏
页码:399 / 402
页数:4
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