Drug Repurposing: New Treatments for Zika Virus infection?

被引：47

作者：

Cheng, Feixiong ^{[1
,2
]}

Murray, James L. ^{[3
]}

Rubin, Donald H. ^{[4
,5
,6
]}

机构：

[1] Northeastern Univ, Ctr Complex Networks Res, Boston, MA 02115 USA

[2] Dana Farber Canc Inst, Ctr Canc Syst Biol, Boston, MA 02215 USA

[3] GeneTAG Technol Inc, Atlanta, GA 30340 USA

[4] Vanderbilt Univ, Sch Med, Dept Med, Div Infect Dis, Nashville, TN 37232 USA

[5] Vanderbilt Univ, Sch Med, Dept Pathol Microbiol & Immunol, Nashville, TN 37232 USA

[6] VA Tennessee Valley Healthcare Syst, Res Med, Nashville, TN 37212 USA

来源：

TRENDS IN MOLECULAR MEDICINE | 2016年 / 22卷 / 11期

关键词：

INHIBITORS; TARGETS;

D O I：

10.1016/j.molmed.2016.09.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

To date, no antiviral agents have been approved for treating Zika virus (ZIKV) infection. Two recent drug-repurposing studies published in Cell Host & Microbe and Nature Medicine demonstrated that screening FDA-approved drugs for antiviral activity is a promising strategy for identifying therapeutics with novel activity against ZIKV infection.

引用

页码：919 / 921

页数：3

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