Gastrulation in zebrafish - all just about adhesion?

被引:107
作者
Solnica-Krezel, Lilianna [1 ]
机构
[1] Vanderbilt Univ, Dept Biol Sci, Nashville, TN 37235 USA
关键词
D O I
10.1016/j.gde.2006.06.009
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
During vertebrate gastrulation, the evolutionarily conserved morphogenetic movements of epilboly, internalization, convergence and extension cooperate to generate germ layers and to sculpt the body plan. In zebrafish, these movements are driven by a variety of cell behaviors, including slow and fast directed migration, radial and mediolateral intercalation, and cell shape changes. Whereas some signaling pathways are required for a subset of these behaviors, other molecules, such as E-cadherin or Gal 2 and Gal 3 proteins, appear to have a widespread role in different gastrulation cell behaviors.
引用
收藏
页码:433 / 441
页数:9
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