Utility of Noninvasive Markers of Fibrosis in Cholestatic Liver Diseases

被引：18

作者：

Corpechot, Christophe ^{[1
,2
]}

机构：

[1] St Antoine Hosp, APHP,Hepatol Dept, Reference Ctr Chron Inflammatory Biliary Dis MIVB, French Network Childhood & Adult Rare Liver Dis F, F-75571 Paris 12, France

[2] Univ Paris 06, INSERM, Fac Med Pierre & Marie Curie, UMR S938, F-75012 Paris, France

来源：

CLINICS IN LIVER DISEASE | 2016年 / 20卷 / 01期

关键词：

Primary biliary cirrhosis; Primary sclerosing cholangitis; Surrogate markers; Elastography; Liver biopsy; Prognosis; PRIMARY BILIARY-CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; CHRONIC HEPATITIS-C; TRANSIENT ELASTOGRAPHY; URSODEOXYCHOLIC ACID; BIOCHEMICAL MARKERS; III PROCOLLAGEN; AMINOTERMINAL PROPEPTIDE; TREATED PATIENTS; SERUM MARKERS;

D O I：

10.1016/j.cld.2015.08.013

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Methods of liver fibrosis assessment have changed considerably in the last 20 years, and noninvasive markers have now been recognized as major first-line tools in the management of patients with chronic viral hepatitis infection. But what about the efficiency and utility of these surrogate indices for the more uncommon chronic cholestatic liver diseases, namely primary biliary cirrhosis and primary sclerosing cholangitis? This article provides clinicians with a global overview of what is currently known in the field. Both diagnostic and prognostic aspects of noninvasive markers of fibrosis in cholestatic liver diseases are presented and discussed.

引用

收藏

页码：143 / +

页数：17

相关论文

共 74 条

[1]

Biochemical markers for non-invasive assessment of disease stage in patients with primary biliary cirrhosis [J].

Alempijevic, Tamara ;

Krstic, Miodrag ;

Jesic, Rada ;

Jovanovic, Ivan ;

Milutinovic, Aleksandra Sokic ;

Kovacevic, Nada ;

Krstic, Slobodan ;

Popovic, Dragan .

WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (05) :591-594

[2]

BABBS C, 1988, LANCET, V1, P1021

[3]

An algorithm for the grading of activity in chronic hepatitis C [J].

Bedossa, P ;

Poynard, T .

HEPATOLOGY, 1996, 24 (02) :289-293

[4]

New paradigms in the treatment of hepatic cholestasis: From UDCA to FXR, PXR and beyond [J].

Beuers, Ulrich ;

Trauner, Michael ;

Jansen, Peter ;

Poupon, Raoul .

JOURNAL OF HEPATOLOGY, 2015, 62 :S25-S37

[5]

A novel panel of blood markers to assess the degree of liver fibrosis [J].

Calès, P ;

Oberti, F ;

Michalak, S ;

Hubert-Fouchard, I ;

Rousselet, MC ;

Konat, A ;

Gallois, Y ;

Ternisien, C ;

Chevailler, A ;

Lunel, F .

HEPATOLOGY, 2005, 42 (06) :1373-1381

[6]

HISTOLOGICAL STAGE IS RELEVANT FOR RISK-STRATIFICATION IN PRIMARY BILIARY CIRRHOSIS [J].

Carbone, M. ;

Sharp, S. J. ;

Heneghan, M. A. ;

Neuberger, J. M. ;

Hirschfield, G. M. ;

Burroughs, A. K. ;

Thorburn, D. ;

Bathgate, A. ;

Aldersley, M. ;

Adgey, C. ;

Trembling, P. ;

Williamson, K. ;

Jopson, L. ;

Lim, R. T. ;

Wareham, N. J. ;

Cordell, H. J. ;

Alexander, G. J. ;

Jones, J. E. ;

Sandford, R. N. ;

Davies, S. E. ;

Mells, G. F. .

JOURNAL OF HEPATOLOGY, 2015, 62 :S805-S805

[7]

Pitfalls of Liver Stiffness Measurement: A 5-Year Prospective Study of 13,369 Examinations [J].

Castera, Laurent ;

Foucher, Juliette ;

Bernard, Pierre-Henri ;

Carvalho, Francoise ;

Allaix, Daniele ;

Merrouche, Wassil ;

Couzigou, Patrice ;

de Ledinghen, Victor .

HEPATOLOGY, 2010, 51 (03) :828-835

[8]

Biochemical markers of liver fibrosis and lymphocytic piecemeal necrosis in UDCA-treated patients with primary biliary cirrhosis [J].

Corpechot, C ;

Poujol-Robert, A ;

Wendum, D ;

Galotte, M ;

Chrétien, Y ;

Poupon, RE ;

Poupon, R .

LIVER INTERNATIONAL, 2004, 24 (03) :187-193

[9]

Primary biliary cirrhosis: Incidence and predictive factors of cirrhosis development in ursodiol-treated patients [J].

Corpechot, C ;

Carrat, F ;

Poupon, R ;

Poupon, RE .

GASTROENTEROLOGY, 2002, 122 (03) :652-658

[10]

Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis [J].

Corpechot, Christophe ;

Abenavoli, Ludovico ;

Rabahi, Nabila ;

Chretien, Yves ;

Andreani, Tony ;

Johanet, Catherine ;

Chazouilleres, Olivier ;

Poupon, Raoul .

HEPATOLOGY, 2008, 48 (03) :871-877

← 1 2 3 4 5 6 7 8 →