Coronary physiology revisited - Practical insights from the cardiac catheterization laboratory

被引：179

作者：

Kern, MJ ^{[1
]}

机构：

[1] St Louis Univ, Hlth Sci Ctr, Dept Internal Med, Div Cardiol, St Louis, MO 63110 USA

来源：

CIRCULATION | 2000年 / 101卷 / 11期

关键词：

physiology; catheterization; heart; coronary blood flow;

D O I：

10.1161/01.CIR.101.11.1344

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Various coronary physiological measurements can be made in the cardiac catheterization laboratory using sensor-tipped guidewires; they include the measurement of poststenotic absolute coronary flow reserve, the relative coronary flow reserve, and the pressure-derived fractional flow reserve of the myocardium. Ambiguity regarding abnormal microcirculation has been reduced or eliminated with measurements of relative coronary flow reserve and fractional flow reserve. The role of microvascular flow impairment can be separately determined with coronary flow velocity reserve measurements. In addition to lesion assessment before and after intervention, emerging applications of coronary physiology include the determination of physiological responses to new pharmacological agents, such as glycoprotein IIb/IIIa blockers, in patients with acute myocardial infarction. Measurements of coronary physiology in the catheterization laboratory provide objective data that complement angiography for clinical decision-making.

引用

页码：1344 / 1351

页数：8

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