A relative weighting method for estimating parameters and variances in multiple data sets

被引:32
作者
Bell, BM
Burke, JV
Schumitzky, A
机构
[1] UNIV WASHINGTON,APPL PHYS LAB,SEATTLE,WA 98195
[2] WASHINGTON UNIV,DEPT MATH,SEATTLE,WA
[3] UNIV SO CALIF,DEPT MATH,LOS ANGELES,CA 90089
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
nonlinear least squares; asymptotic statistics;
D O I
10.1016/0167-9473(95)00043-7
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
We are given multiple data sets and a nonlinear model function for each data value. Each data value is the sum of its error and its model function evaluated at an unknown parameter vector. The data errors are mean zero, finite variance, independent, are not necessarily normal and are identically distributed within each data set. We consider the problem of estimating the data variance as well as the parameter vector via an extended least-squares technique motivated by maximum likelihood estimation. We prove convergence of an algorithm that generalizes a standard successive approximation algorithm from nonlinear programming. This generalization reduces the estimation problem to a sequence of linear least-squares problems. It is shown that the parameter and variance estimators converge to their true values as the number of data values goes to infinity. Moreover, if the constraints are not active, the parameter estimates converge in distribution, This convergence does not depend on the data errors being normally distributed.
引用
收藏
页码:119 / 135
页数:17
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