Modification of tonotopic representation in the auditory system during development

During the early development of the bird and the mammalian peripheral auditory system, a restricted range of low-mid frequencies is recorded in immature animals. These early recordings are correlated to the base or mid-basal region of the cochlea which codes high frequencies in the adult. In order to reconcile the functional observations with anatomical ones, two main hypotheses have been put forward: one called the development of the place principle derived from observations of acoustic trauma in chick cochlea and a second derived from auditory nerve fiber recordings in kittens. Whatever the theories, the tonotopic shift during development is a well-established phenomenon in both birds and mammals that could be explained by a synthetic theory including active and passive cochlear processes. The tonotopic shift observed in the central auditory system mimics quite closely the frequency representation of the peripheral auditory system. The same trend is observed in all auditory nuclei including the cortex, except that the frequency representation is more complex because it shows tonotopic maps that can be twisted in three dimensions. From current observations, there is a simultaneous onset of tonotopic maps across auditory nuclei up to the cortex. A hypothesis is presented related to the frequency changes observed in the cochlea that affect the central auditory pathway, along with possible consequences on auditory behavior. (C) 1997 Elsevier Science Ltd.