Carcinogenic effects of polychlorinated biphenyls

被引：41

作者：

Faroon, OM ^{[1
]}

Keith, S ^{[1
]}

Jones, D ^{[1
]}

De Rosa, C ^{[1
]}

机构：

[1] US Dept Hlth & Human Serv, Agcy Tox Subst & Dis Registry, Div Toxicol, Atlanta, GA 30333 USA

来源：

TOXICOLOGY AND INDUSTRIAL HEALTH | 2001年 / 17卷 / 02期

关键词：

biliary tract cancer; breast cancer; cancer; congener; liver cancer; mixtures; non-Hodgkin lymphoma; PCBs; skin cancer;

D O I：

10.1191/0748233701th098oa

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These profiles comprehensively summarize toxicological and environmental information. This article constitutes the release of an important section of the Toxicological profile for polychlorinated biphenyls [ATSDR. 2000: Toxicological profile for polychlorinated biphenyls. Atlanta, GA: US Department of Health and Human Services, Agency for Toxic Substances and Disease Registry.] into the scientific literature. This article focuses on the carcinogenic effects of this group of synthetic organic chemicals (polychlorinated biphenyls) in humans and animals. Information on other health effects, toxicokinetics, mechanisms of toxicity, biomarkers, interactions, chemical and physical properties, potential for human exposure, and regulations and advisories is detailed in the profile.

引用

页码：41 / 62

页数：22

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