Synthesis of highly functionalized γ-lactones via 1,5-electrocyclic ring closure

被引：13

作者：

Anac, Olca ^{[1
]}

Gungor, F. Seyma ^{[1
]}

Merey, Gokce ^{[1
]}

机构：

[1] Tech Univ Istanbul, Fac Sci & Letters, Dept Chem, TR-34469 Istanbul, Turkey

来源：

HELVETICA CHIMICA ACTA | 2006年 / 89卷 / 06期

关键词：

D O I：

10.1002/hlca.200690120

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have investigated 1,5-electrocyclic ring-closure reactions of conjugated esters with dimethyl diazomalonate in the presence of [Cu(acac)(2)] as catalyst. Our new protocol offers an easy entry to various polyfunctionalized gamma-lactones in high yields. Their subsequent derivatives may be used as valuable intermediates, especially in the synthesis of natural products and their analogues.

引用

页码：1231 / 1240

页数：10

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