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Steering anti-cancer drugs away from the TRAIL

被引：48
作者：
Nagata, S
机构：
[1] Osaka Univ, Sch Med, Dept Genet, Suita, Osaka 5650871, Japan
[2] Japan Sci & Technol Corp, Core Res Evolut Sci & Technol, Suita, Osaka 5650871, Japan
来源：
NATURE MEDICINE | 2000年 / 6卷 / 05期
关键词：
D O I：
10.1038/74972
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
TRAIL, a cytokine of the TNF family, has been hyped as an almost 'magical' drug for cancer treatment. However, its possible side effects in the liver raise serious concerns about its likelihood for development into a safe therapeutic product (pages 564-567).
引用
收藏
页码：502 / 503
页数：2
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