Dendritic phosphoramidite ligands in Rh-catalysed asymmetric hydrogenations

被引：30

作者：

Botman, PNM

Amore, A

van Heerbeek, R

Back, JW

Hiemstra, H

Reek, JNH

van Maarseveen, JH

机构：

[1] Univ Amsterdam, Vant Hoff Inst Mol Sci, NL-1018 WS Amsterdam, Netherlands

[2] Univ Amsterdam, Swammerdam Inst Life Sci, Mass Spectrometry Grp, NL-1018 WV Amsterdam, Netherlands

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 31期

关键词：

dendrimers; homogeneous catalysis; asymmetric hydrogenations; phosphoramidite ligands;

D O I：

10.1016/j.tetlet.2004.06.040

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The axially chiral BICOL backbone was functionalised with two third generation carbosilane dendritic wedges and further elaborated to a phosphoramidite ligand. High enantioselectivities were obtained when these monodentate ligands were applied in the rhodium-catalysed asymmetric hydrogenation of methyl 2-acetamidocinnamate. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：5999 / 6002

页数：4

共 28 条

[1]

[Anonymous], 1993, HDB ENANTIOSELECTIVE

[2] Dendritic catalysts and dendrimers in catalysis [J].

Astruc, D ;

Chardac, F .

CHEMICAL REVIEWS, 2001, 101 (09) :2991-3023

[3]

Botman PNM, 2002, EUR J ORG CHEM, V2002, P1952, DOI 10.1002/1099-0690(200206)2002:12<1952::AID-EJOC1952>3.0.CO

[4]

2-L

[5] C2-SYMMETRICAL BIS(PHOSPHOLANES) AND THEIR USE IN HIGHLY ENANTIOSELECTIVE HYDROGENATION REACTIONS [J].

BURK, MJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (22) :8518-8519

[6]

Chaloner P A., 1994, Homogeneous Hydrogenation, DOI [DOI 10.1007/978-94-017-1791-5, 10.1007/978-94-017-1791-5]

[7]

Claver C, 2000, CHEM COMMUN, P961

[8] ASYMMETRIC SYNTHESIS OF HYDRATROPIC ACID AND AMINO-ACIDS BY HOMOGENEOUS CATALYTIC HYDROGENATION [J].

DANG, TP ;

KAGAN, HB .

JOURNAL OF THE CHEMICAL SOCIETY D-CHEMICAL COMMUNICATIONS, 1971, (10) :481-&

[9]

Deng GJ, 2002, CHINESE J CHEM, V20, P1139

[10] Highly effective and recyclable dendritic BINAP ligands for asymmetric hydrogenation [J].

Fan, QH ;

Chen, YM ;

Chen, XM ;

Jiang, DZ ;

Xi, F ;

Chan, ASC .

CHEMICAL COMMUNICATIONS, 2000, (09) :789-790

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