Bioactive ceramic-based materials with designed reactivity for bone tissue regeneration

被引：136

作者：

Ohtsuki, Chikara ^{[1
]}

Kamitakahara, Masanobu ^{[2
]}

Miyazaki, Toshiki ^{[3
]}

机构：

[1] Nagoya Univ, Dept Crystalline Mat Sci, Grad Sch Engn, Chikusa Ku, Nagoya, Aichi 4648603, Japan

[2] Tohoku Univ, Grad Sch Environm Studies, Aoba Ku, Sendai, Miyagi 9808579, Japan

[3] Kyushu Inst Technol, Grad Sch Life Sci & Syst Engn, Wakamatsu Ku, Kitakyushu, Fukuoka 8080196, Japan

来源：

JOURNAL OF THE ROYAL SOCIETY INTERFACE | 2009年 / 6卷

关键词：

ceramics; bioactivity; hydroxyapatite; calcium phosphate; hybrid; coating; APATITE-FORMING ABILITY; SIMULATED BODY-FLUID; POLYDIMETHYLSILOXANE (PDMS)-CAO-SIO2 HYBRIDS; TRICALCIUM PHOSPHATE; MECHANICAL-PROPERTIES; ALPHA-TRICALCIUM; CALCIUM-PHOSPHATE; POLYAMIDE FILMS; GLASS-CERAMICS; IN-VITRO;

D O I：

10.1098/rsif.2008.0419.focus

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];

摘要：

Bioactive ceramics have been used clinically to repair bone defects owing to their biological affinity to living bone; i.e. the capability of direct bonding to living bone, their so-called bioactivity. However, currently available bioactive ceramics do not satisfy every clinical application. Therefore, the development of novel design of bioactive materials is necessary. Bioactive ceramics show osteoconduction by formation of biologically active bone-like apatite through chemical reaction of the ceramic surface with surrounding body fluid. Hence, the control of their chemical reactivity in body fluid is essential to developing novel bioactive materials as well as biodegradable materials. This paper reviews novel bioactive materials designed based on chemical reactivity in body fluid.

引用

页码：S349 / S360

页数：12

共 87 条

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