Reversing the tuberculosis upwards trend: a success story in Romania

被引:13
作者
Marica, C. [2 ]
Didilescu, C. [2 ]
Galie, N. [2 ]
Chiotan, D. [2 ]
Zellweger, J. P. [3 ]
Sotgiu, G. [4 ]
D'Ambrosio, L. [1 ]
Centis, R. [1 ]
Ditiu, L. [5 ]
Migliori, G. B. [1 ]
机构
[1] Fdn S Maugeri Care & Res Inst, WHO, Collaborating Ctr TB & Lung Dis, I-21049 Tradate, Italy
[2] Natl Inst Marius Nasta, Bucharest, Romania
[3] Swiss Lung Assoc, Bern, Switzerland
[4] Univ Sassari, Inst Hyg & Prevent Med, I-07100 Sassari, Italy
[5] WHO, Reg Off Europe, DK-2100 Copenhagen, Denmark
关键词
Epidemiology; incidence; Romania; success rate; targets; tuberculosis;
D O I
10.1183/09031936.00104308
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
100201 [内科学];
摘要
At present, no published evidence is available on the effectiveness of the DOTS (directly observed treatment, short-course) strategy in reducing the incidence of tuberculosis (TB) within a country in the European "hot spots". The present study aimed to demonstrate the effectiveness of the strategy implementation in reversing the epidemiological TB trend in Romania based on programmatic data analysis. Key programme indicators were analysed from 1998 to 2007, and included DOTS coverage, case-detection rate, treatment success and overall incidence of notified cases. Internationally agreed definitions were used. The key programme indicators began declining and the World Health Assembly targets were reached (79% case-detection of new sputum-smear positive cases and 85.5% success rate in new culture-positive TB cases), 7 yrs after initiation of the DOTS expansion. The success story in Romania suggests that other middle-income, high-incidence countries (i.e. those belonging to the former Soviet Union) might be able to reach the World Health Assembly Targets and curb the burden of tuberculosis.
引用
收藏
页码:168 / 170
页数:3
相关论文
共 10 条
[1]
[Anonymous], 2008, GLOBAL TUBERCULOSIS
[2]
Long term efficacy of DOTS regimens for tuberculosis: systematic review [J].
Cox, Helen S. ;
Morrow, Martha ;
Deutschmann, Peter W. .
BMJ-BRITISH MEDICAL JOURNAL, 2008, 336 (7642) :484-487
[3]
*EUROTB NAT COORD, 2008, SURV TUB EUR REP TUB
[4]
International standards for tuberculosis care [J].
Hopewell, Philip C. ;
Pai, Madhukar ;
Maher, Dermot ;
Uplekar, Mukund ;
Raviglione, Mario C. .
LANCET INFECTIOUS DISEASES, 2006, 6 (11) :710-725
[5]
European surveillance of tuberculosis: description of the network and recent results [J].
Infuso, A ;
Falzon, D .
MEDECINE ET MALADIES INFECTIEUSES, 2005, 35 (05) :264-268
[6]
125 years after Robert Koch's discovery of the tubercle bacillus: the new XDR-TB threat. Is "science" enough to tackle the epidemic? [J].
Migliori, G. B. ;
Loddenkemper, R. ;
Blasi, F. ;
Raviglione, M. C. .
EUROPEAN RESPIRATORY JOURNAL, 2007, 29 (03) :423-427
[7]
WHO's new Stop TB Strategy [J].
Raviglione, MC ;
Uplekar, MW .
LANCET, 2006, 367 (9514) :952-955
[8]
Progress of DOTS in global tuberculosis control [J].
Sharma, SK ;
Liu, JJ .
LANCET, 2006, 367 (9514) :951-952
[9]
Sotgiu G, 2008, INT J TUBERC LUNG D, V12, P606
[10]
Stop TB Partnership, 2006, GLOB PLAN STOP TB 20