Microchip technologies for the analysis of biological cells

被引：12

作者：

Ichiki, T

Shinbashi, S

Ujiie, T

Horiike, Y

机构：

[1] Toyo Univ, Dept Elect & Elect Engn, Kawagoe, Saitama 3508585, Japan

[2] Univ Tokyo, Dept Mat Sci, Bunkyo Ku, Tokyo 1138656, Japan

来源：

JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY | 2002年 / 15卷 / 03期

关键词：

microchip; microelectrode; biological cell; dielectrophoretic manipulation; single-cell impedance measurement;

D O I：

10.2494/photopolymer.15.487

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

In the post-genome era, the importance of cell analysis is increasingly appreciated since the cell is the minimum unit of the life phenomena. On-chip manipulation and measurement of biological cells are recognized to be an important subject for the establishment of novel analytical tools and methodologies for the forthcoming new cell biology. In this paper on-chip manipulation of biological cells and microparticles by means of dielectrophoresis and on-chip detection of single biological cells by ac impedance spectrometry have been investigated using microfulidics devices with embedded microelectrodes which were fabricated by LSI compatible microfabrication technologies.

引用

页码：487 / 492

页数：6

共 21 条

[1]

Alberts B., 1994, MOL BIOL CELL

[2] Electric impedance spectroscopy using microchannels with integrated metal electrodes [J].