A delay in CD4 cell response after initiation of highly active antiretroviral therapy is associated with the presence of anti-cytomegalovirus but not with anti-herpes simplex virus antibodies

被引：7

作者：

Goossens, VJ ^{[1
]}

Schreij, G

van der Geest, S

van Leeuwen, DM

Baas, DC

Bruggeman, CA

van der Ven, AJ

机构：

[1] Univ Hosp Maastricht, Dept Med Microbiol, Maastricht, Netherlands

[2] Univ Hosp Maastricht, Dept Internal Med, Maastricht, Netherlands

来源：

AIDS | 2002年 / 16卷 / 12期

关键词：

D O I：

10.1097/00002030-200208160-00015

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

After the successful initiation of highly active antiretroviral therapy (HAART) in HIV-1-infected patients, the mean CD4 cell response was lower in cytomegalovirus (CMV)-seropositive patients than in CMV-seronegative patients (P < 0.05). The difference between the mean CD4 cell counts of CMV-seronegative and CMV-seropositive patients was maximal (163 X 10(6)/l) at 76 weeks after the start of HAART, and decreased gradually thereafter. No association was found between herpes simplex virus types 1 and 2 serostatus and CD4 cell response.

引用

页码：1682 / 1684

页数：3

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