Sezary syndrome: Diagnostic criteria and therapeutic options

被引:16
作者
Russell-Jones, R [1 ]
Whittaker, S [1 ]
机构
[1] St Thomas Hosp, St Johns Inst Dermatol, Skin Tumour Unit, London SE1 7EH, England
关键词
D O I
10.1016/S1085-5629(00)80006-1
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Sezary syndrome (SS) is a rare form of erythrodermic cutaneous T-cell lymphoma with hematological involvement and a poor prognosis. Therapies include photopheresis, with or without interferon, chemotherapy, and total skin electron beam therapy. The lack of any randomized studies makes it difficult to assess the effect of current therapy on survival. In addition, the different response rates reported for individual treatments may depend as much on the criteria used to define SS as the therapy itself. This article reviews the diagnostic tests that are needed to reliably diagnose SS and offers a critical analysis of current treatment options, Copyright (C) 2000 by W.B. Saunders Company.
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收藏
页码:100 / 108
页数:9
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