Twenty-One-Gene Assay: Challenges and Promises in Translating Personal Genomics and Whole-Genome Scans Into Personalized Treatment of Breast Cancer

被引：64

作者：

Roukos, Dimitrios H. ^{[1
]}

机构：

[1] Univ Ioannina, Sch Med, Surg Oncol Res Unit, Dept Surg, GR-45110 Ioannina, Greece

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2009年 / 27卷 / 08期

关键词：

GENE-EXPRESSION; GASTRIC-CANCER; CHEMOTHERAPY; PREVENTION; PREDICTION;

D O I：

10.1200/JCO.2008.20.2812

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1337 / 1338

页数：2

共 17 条

[1] Molecular medicine, gene-expression profiling and molecular diagnostics: putting the cart before the horse [J].

Bustin, Stephen A. .

BIOMARKERS IN MEDICINE, 2008, 2 (03) :201-207

[2] Progress and promise:: highlights of the international expert consensus on the primary therapy of early breast cancer 2007 [J].

Goldhirsch, A. ;

Wood, W. C. ;

Gelber, R. D. ;

Coates, A. S. ;

Thuerlimann, B. ;

Senn, H.-J. ;

Members, Panel .

ANNALS OF ONCOLOGY, 2007, 18 (07) :1133-1144

[3] Prognostic utility of the 21-gene assay in hormone receptor-positive operable breast cancer compared with classical clinicopathologic features [J].

Goldstein, Lori J. ;

Gray, Robert ;

Badve, Sunil ;

Childs, Barrett H. ;

Yoshizawa, Carl ;

Rowley, Steve ;

Shak, Steven ;

Baehner, Frederick L. ;

Ravdin, Peter M. ;

Davidson, Nancy E. ;

Sledge, George W., Jr. ;

Perez, Edith A. ;

Shulman, Lawrence N. ;

Martino, Silvana ;

Sparano, Joseph A. .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (25) :4063-4071

[4] Letting the genome out of the bottle - Will we get our wish? [J].

Hunter, David J. ;

Khoury, Muin J. ;

Drazen, Jeffrey M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (02) :105-107

[5] Gene expression profiling for individualized breast cancer chemotherapy: success or not? [J].

Ioannidis, John P. A. .

NATURE CLINICAL PRACTICE ONCOLOGY, 2006, 3 (10) :538-539

[6] A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer [J].

Paik, S ;

Shak, S ;

Tang, G ;

Kim, C ;

Baker, J ;

Cronin, M ;

Baehner, FL ;

Walker, MG ;

Watson, D ;

Park, T ;

Hiller, W ;

Fisher, ER ;

Wickerham, DL ;

Bryant, J ;

Wolmark, N .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (27) :2817-2826

[7] Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer [J].

Paik, Soonmyung ;

Tang, Gong ;

Shak, Steven ;

Kim, Chungyeul ;

Baker, Joffre ;

Kim, Wanseop ;

Cronin, Maureen ;

Baehner, Frederick L. ;

Watson, Drew ;

Bryant, John ;

Costantino, Joseph P. ;

Geyer, Charles E., Jr. ;

Wickerham, D. Lawrence ;

Wolmark, Norman .

JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (23) :3726-3734

[8] Polygenes, risk prediction, and targeted prevention of breast cancer [J].

Pharoah, Paul D. P. ;

Antoniou, Antonis C. ;

Easton, Douglas F. ;

Ponder, Bruce A. J. .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (26) :2796-2803

[9] Genetics and genome-wide association studies: surgery-guided algorithm and promise for future breast cancer personalized surgery [J].

Roukos, Dimitricis H. .

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 2008, 8 (05) :587-597

[10] Genomics and challenges toward personalized breast cancer local control [J].

Roukos, Dimitrios H. ;

Lykoudis, Efstathios ;

Liakakos, Theodore .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (26) :4360-4361

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