Genetics of Type 1A Diabetes

被引：359

作者：

Concannon, Patrick ^{[1
,2
]}

Rich, Stephen S. ^{[1
,3
]}

Nepom, Gerald T. ^{[4
]}

机构：

[1] Univ Virginia, Ctr Publ Hlth Genom, Charlottesville, VA 22908 USA

[2] Univ Virginia, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

[3] Univ Virginia, Dept Publ Hlth Sci, Charlottesville, VA 22908 USA

[4] Benaroya Res Inst, Diabet Res Program, Seattle, WA USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2009年 / 360卷 / 16期

基金：

美国国家卫生研究院;

关键词：

GENOME-WIDE ASSOCIATION; LYMPHOID TYROSINE PHOSPHATASE; RHEUMATOID-ARTHRITIS; SUSCEPTIBILITY LOCUS; AUTOIMMUNE-DISEASE; MULTIPLEX FAMILIES; NONSYNONYMOUS SNPS; R620W POLYMORPHISM; MELLITUS; PTPN22;

D O I：

10.1056/NEJMra0808284

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1646 / 1654

页数：9

共 55 条

[1] Genetic prediction of autoimmunity: Initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4-DQ8 relatives of patients with type 1A diabetes [J].

Aly, TA ;

Ide, A ;

Humphrey, K ;

Barker, JM ;

Steck, A ;

Erlich, HA ;

Yu, LP ;

Miao, DM ;

Redondo, MJ ;

McFann, K ;

Roberts, CM ;

Babu, SR ;

Norris, JM ;

Eisenbarth, GS ;

Rewers, MJ .

JOURNAL OF AUTOIMMUNITY, 2005, 25 :40-45

[2] Extreme genetic risk for type 1A diabetes [J].

Aly, Theresa A. ;

Ide, Akane ;

Jahromi, Mohamed M. ;

Barker, Jennifer M. ;

Fernando, Maria S. ;

Babu, Sunanda R. ;

Yu, Liping ;

Miao, Dongmei ;

Erlich, Henry A. ;

Fain, Pamela R. ;

Barriga, Katherine J. ;

Norris, Jill M. ;

Rewers, Marian J. ;

Eisenbarth, George S. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (38) :14074-14079

[3]

[Anonymous], 1976, GENETICS DIABETES

[4] Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY) [J].

Barker, JM ;

Barriga, KJ ;

Yu, LP ;

Miao, DM ;

Erlich, HA ;

Norris, JM ;

Eisenbarth, GS ;

Rewers, M .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (08) :3896-3902

[5] DIABETES IN IDENTICAL-TWINS - A STUDY OF 200 PAIRS [J].

BARNETT, AH ;

EFF, C ;

LESLIE, RDG ;

PYKE, DA .

DIABETOLOGIA, 1981, 20 (02) :87-93

[6] A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis [J].

Begovich, AB ;

Carlton, VEH ;

Honigberg, LA ;

Schrodi, SJ ;

Chokkalingam, AP ;

Alexander, HC ;

Ardlie, KG ;

Huang, QQ ;

Smith, AM ;

Spoerke, JM ;

Conn, MT ;

Chang, M ;

Chang, SYP ;

Saiki, RK ;

Catanese, JJ ;

Leong, DU ;

Garcia, VE ;

McAllister, LB ;

Jeffery, DA ;

Lee, AT ;

Batliwalla, F ;

Remmers, E ;

Criswell, LA ;

Seldin, MF ;

Kastner, DL ;

Amos, CI ;

Sninsky, JJ ;

Gregersen, PK .

AMERICAN JOURNAL OF HUMAN GENETICS, 2004, 75 (02) :330-337

[7] A POLYMORPHIC LOCUS NEAR THE HUMAN INSULIN GENE IS ASSOCIATED WITH INSULIN-DEPENDENT DIABETES-MELLITUS [J].

BELL, GI ;

HORITA, S ;

KARAM, JH .

DIABETES, 1984, 33 (02) :176-183

[8] The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 [J].

Bennett, CL ;

Christie, J ;

Ramsdell, F ;

Brunkow, ME ;

Ferguson, PJ ;

Whitesell, L ;

Kelly, TE ;

Saulsbury, FT ;

Chance, PF ;

Ochs, HD .

NATURE GENETICS, 2001, 27 (01) :20-21

[9] TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs [J].

Bisikirska, B ;

Colgan, J ;

Luban, J ;

Bluestone, JA ;

Herold, KC .

JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (10) :2904-2913

[10] A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes [J].

Bottini, N ;

Musumeci, L ;

Alonso, A ;

Rahmouni, S ;

Nika, K ;

Rostamkhani, M ;

MacMurray, J ;

Meloni, GF ;

Lucarelli, P ;

Pellecchia, M ;

Eisenbarth, GS ;

Comings, D ;

Mustelin, T .

NATURE GENETICS, 2004, 36 (04) :337-338

← 1 2 3 4 5 6 →