Further membranolide diterpenes from the Antarctic sponge Dendrilla membranosa

被引：38

作者：

Ankisetty, S

Amsler, CD

McClintock, JB

Baker, BJ

机构：

[1] Univ S Florida, Dept Chem, Tampa, FL 33620 USA

[2] Univ Alabama Birmingham, Dept Biol Sci, Birmingham, AL 35294 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 07期

关键词：

D O I：

10.1021/np0340551

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Chemical investigation of the Antarctic sponge Dendrilla membranosa collected from the vicinity of Palmer Station on Anvers Island, Antarctica, yielded three new diterpenes, membranolides B-D (2-4), as well as three previously reported sponge metabolites. Membranolides C and D (3, 4), bearing carboxylic acid functional groups, display Gram-negative antibiotic and antifungal activities.

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页码：1172 / 1174

页数：3

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