PCSK9, from gene to protein:: a new actor involved in cholesterol homeostasis

[1] Mutations in PCSK9 cause autosomal dominant hypercholesterolemia [J]. NATURE GENETICS, 2003, 34 (02) : 154 - 156

[2] Allard Delphine, 2005, Hum Mutat, V26, P497, DOI 10.1002/humu.9383

[3] Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2006, 26 (05) : 1094 - 1100

[4] Effect of mutations in the PCSK9 gene on the cell surface LDL receptors [J]. HUMAN MOLECULAR GENETICS, 2006, 15 (09) : 1551 - 1558

[5] Low LDL cholesterol in African Americans resulting from frequent nonsense mutations in PCSK9 [J]. NATURE GENETICS, 2005, 37 (03) : 328 - 328

[6] Sequence variations in PCSK9, low LDL, and protection against coronary heart disease [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (12) : 1264 - 1272

[7] Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2004, 24 (08) : 1454 - 1459

[8] A spectrum of PCSK9 Alleles contributes to plasma levels of low-density lipoprotein cholesterol [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2006, 78 (03) : 410 - 422

[9] Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia [J]. CLINICAL GENETICS, 2004, 65 (05) : 419 - 422

[10] Proprotein convertase subtilisin kexin 9: the third locus implicated in autosomal dominant hypercholesterolemia [J]. CURRENT OPINION IN LIPIDOLOGY, 2005, 16 (02) : 167 - 172

[1] Mutations in PCSK9 cause autosomal dominant hypercholesterolemia [J]. NATURE GENETICS, 2003, 34 (02) : 154 - 156

[2] Allard Delphine, 2005, Hum Mutat, V26, P497, DOI 10.1002/humu.9383

[3] Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2006, 26 (05) : 1094 - 1100

[4] Effect of mutations in the PCSK9 gene on the cell surface LDL receptors [J]. HUMAN MOLECULAR GENETICS, 2006, 15 (09) : 1551 - 1558

[5] Low LDL cholesterol in African Americans resulting from frequent nonsense mutations in PCSK9 [J]. NATURE GENETICS, 2005, 37 (03) : 328 - 328

[6] Sequence variations in PCSK9, low LDL, and protection against coronary heart disease [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (12) : 1264 - 1272

[7] Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2004, 24 (08) : 1454 - 1459

[8] A spectrum of PCSK9 Alleles contributes to plasma levels of low-density lipoprotein cholesterol [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2006, 78 (03) : 410 - 422

[9] Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia [J]. CLINICAL GENETICS, 2004, 65 (05) : 419 - 422

[10] Proprotein convertase subtilisin kexin 9: the third locus implicated in autosomal dominant hypercholesterolemia [J]. CURRENT OPINION IN LIPIDOLOGY, 2005, 16 (02) : 167 - 172