Clinical Effects of Hypertension on the Mortality of Patients with Acute Myocardial Infarction

被引:28
作者
Kong, Dong Goo [1 ]
Jeong, Myung Ho [2 ]
Ahn, Yongkeun [2 ]
Chae, Shung Chull [3 ]
Hur, Seung Ho [4 ]
Hong, Taek Jong [5 ]
Kim, Young Jo [6 ]
Seong, In Whan [7 ]
Chae, Jei Keon [8 ]
Rhew, Jay Young [9 ]
Chae, In Ho [10 ]
Cho, Myeong Chan [11 ]
Bae, Jang Ho [12 ]
Rha, Seung Woon [13 ]
Kim, Chong Jin [14 ]
Jang, Yang Soo [15 ]
Yoon, Junghan [16 ]
Seung, Ki Bae [17 ]
Park, Seung Jung [18 ]
机构
[1] Kwangju Christian Hosp, Kwangju, South Korea
[2] Chonnam Natl Univ, Kwangju 501757, South Korea
[3] Kyungpook Natl Univ, Taegu, South Korea
[4] Keimyung Univ, Dongsan Med Ctr, Taegu, South Korea
[5] Pusan Natl Univ Hosp, Pusan, South Korea
[6] Yeungnam Univ Hosp, Taegu, South Korea
[7] Chungnam Natl Univ Hosp, Taejon, South Korea
[8] Chonbuk Natl Univ Hosp, Jeonju, South Korea
[9] Jeonju Presbyterian Med Ctr, Jeonju, South Korea
[10] Seoul Natl Univ, Bundang Hosp, Seongam, South Korea
[11] Chungbuk Natl Univ, Cheongju, South Korea
[12] Konyang Univ, Taejon, South Korea
[13] Korea Univ, Guro Hosp, Seoul, South Korea
[14] Kyunghee Univ Hosp, Seoul, South Korea
[15] Yonsei Univ, Severance Hosp, Seoul 120749, South Korea
[16] Wonju Univ Hosp, Wonju, South Korea
[17] Catholic Univ, St Marys Hosp, Seoul, South Korea
[18] Univ Ulsan, Asan Med Ctr, Seoul, South Korea
关键词
Hypertension; Myocardial infarction; Mortality; VENTRICULAR SYSTOLIC DYSFUNCTION; CORONARY-HEART-DISEASE; BLOOD-PRESSURE; RISK-FACTORS; ANTECEDENT HYPERTENSION; ELDERLY-PATIENTS; OUTCOMES; FAILURE; CAPTOPRIL; INSIGHTS;
D O I
10.3346/jkms.2009.24.5.800
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
The incidence of ischemic heart disease has been increased rapidly in Korea. However, the clinical effects of antecedent hypertension on acute myocardial infarction have not been identified. We assessed the relationship between antecedent hypertension and clinical outcomes in 7,784 patients with acute myocardial infarction in the Korea Acute Myocardial Infarction Registry during one-year follow-up. Diabetes mellitus, hyperlipidemia, cerebrovascular disease, heart failure, and peripheral artery disease were more prevalent in hypertensives (n=3,775) than nonhypertensives (n=4,009). During hospitalization, hypertensive patients suffered from acute renal failure, shock, and cerebrovascular event more frequently than in nonhypertensives. During follow-up of one-year, the incidence of major adverse cardiac events was higher in hypertensives. In multi-variate adjustment, old age, Killip class >= III, left ventricular ejection fraction <45%, systolic blood pressure <90 mmHg on admission, post procedural TIMI flow grade <= 2, female sex, and history of hypertension were independent predictors for in-hospital mortality. However antecedent hypertension was not significantly associated with one-year mortality. Hypertension at the time of acute myocardial infarction is associated with an increased rate of in-hospital mortality.
引用
收藏
页码:800 / 806
页数:7
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