An improved protocol for the preparation of 3-pyridyl- and some arylboronic acids

被引：172

作者：

Li, WJ ^{[1
]}

Nelson, DP ^{[1
]}

Jensen, MS ^{[1
]}

Hoerrner, RS ^{[1
]}

Cai, DW ^{[1
]}

Larsen, RD ^{[1
]}

Reider, PJ ^{[1
]}

机构：

[1] Merck Res Labs, Proc Res Dept, Rahway, NJ 07065 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 15期

关键词：

D O I：

10.1021/jo025792p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Pyridylboronic acid was prepared in high yield and bulk quantity from 3-bromopyridine via a protocol of lithium-halogen exchange and "in situ quench". This technique was further studied and evaluated on other aryl halides in the preparation of arylboronic acids.

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收藏

页码：5394 / 5397

页数：4

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