ESPEN Guidelines on Parenteral Nutrition: Hepatology

被引：306

作者：

Plauth, Mathias ^{[1
]}

Cabre, Eduard ^{[2
]}

Campillo, Bernard ^{[3
]}

Kondrup, Jens ^{[4
]}

Marchesini, Giulio ^{[5
]}

Schuetz, Tatjana ^{[6
]}

Shenkin, Alan ^{[7
]}

Wendon, Julia ^{[8
]}

机构：

[1] Klinikum Stadt Ludwigshafen, Dessau, Germany

[2] Hosp Badalona Germans Trias & Pujol, Badalona, Spain

[3] Hop Albert Chenevier, Paris, France

[4] Rigshosp, DK-2100 Copenhagen, Denmark

[5] Univ Bologna, Azienda Osped Bologna, Bologna, Italy

[6] Charite, D-13353 Berlin, Germany

[7] Univ Liverpool, Liverpool L69 3BX, Merseyside, England

[8] Kings Coll Hosp London, London, England

来源：

CLINICAL NUTRITION | 2009年 / 28卷 / 04期

关键词：

Alcoholic; Steatohepatitis; Liver; Cirrhosis; Electrolytes; Vitamins; ACUTE LIVER-FAILURE; RESTING ENERGY-EXPENDITURE; CHAIN AMINO-ACIDS; PROTEIN-CALORIE MALNUTRITION; RANDOMIZED CONTROLLED-TRIAL; SEVERE ALCOHOLIC HEPATITIS; INTENSIVE INSULIN THERAPY; ORAL ZINC SUPPLEMENTATION; PRIMARY BILIARY-CIRRHOSIS; DOUBLE-BLIND;

D O I：

10.1016/j.clnu.2009.04.019

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

Parenteral nutrition (PN) offers the possibility to increase or to ensure nutrient intake in patients, in whom sufficient nutrition by oral or enteral alone is insufficient or impossible. Complementary to the ESPEN guideline on enteral nutrition of liver disease (LD) patients the present guideline is intended to give evidence-based recommendations for the use of PN in LID. For this purpose three paradigm conditions of LID were chosen: alcoholic steatohepatitis (ASH), liver cirrhosis and acute liver failure. The guideline was developed by an interdisciplinary expert group in accordance with officially accepted standards and is based on all relevant publications since 1985. The guideline was presented on the ESPEN website and visitors' criticism and suggestions were welcome and included in the final revision. PN improves nutritional state and liver function in malnourished patients with ASH. PN is safe and improves mental state in patients with cirrhosis and severe HE. Perioperative (including liver transplantation) PN is safe and reduces the rate of complications. In acute liver failure PN is a safe second-line option to adequately feed patients in whom enteral nutrition is insufficient or impossible. (C) 2009 European Society for Clinical Nutrition and Metabolism. All rights reserved.

引用

页码：436 / 444

页数：9

共 147 条

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