Subcutaneous botulinum toxin type A inhibits regional sweating: An individual observation

被引：20

作者：

Cheshire, WP ^{[1
]}

机构：

[1] MAYO CLIN JACKSONVILLE,DEPT NEUROL,JACKSONVILLE,FL 32224

来源：

CLINICAL AUTONOMIC RESEARCH | 1996年 / 6卷 / 02期

关键词：

botulinum toxin; swearing; sympathetic nervous system;

D O I：

10.1007/BF02291235

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Botulinum toxin inhibits neuromuscular transmission by blocking the exocytosis of acetylcholine. It was tested for a similar effect on cholinergic postganglionic sympathetic neurones at the sudomotor junction. Subcutaneous injections of 0.1 and 1.0 units of type A botulinum toxin into the forearm of a healthy subject abolished local thermoregulatory swearing in cutaneous regions spanning 1.0 and 1.5 cm for nearly 1 year without producing weakness. Botulinum toxin, therefore appears to have potent anhidrotic activity.

引用

页码：123 / 124

页数：2

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