Asymmetric catalytic alkylation of aldehydes with diethylzinc using a chiral binaphthol-titanium complex

被引：186

作者：

Mori, M ^{[1
]}

Nakai, T ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT CHEM TECHNOL,MEGURO KU,TOKYO 152,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 35期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/S0040-4039(97)01433-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The asymmetric catalytic alkylation of aldehydes with diethylzinc using (R)-BINOL-Ti(O-i-Pr)(2) complex as an asymmetric precatalyst is shown to afford the corresponding secondary alcohols in a high enantioselectivity (up to 86% ee). (C) 1997 Elsevier Science Ltd.

引用

页码：6233 / 6236

页数：4

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