Thorough investigation of the oxygen heterocyclic fraction of lime (Citrus aurantifolia (Christm.) Swingle) juice

被引:18
作者
Costa, Rosaria [1 ]
Russo, Marina [1 ]
De Grazia, Selenia [1 ]
Grasso, Elisa [1 ]
Dugo, Paola [1 ,2 ,3 ]
Mondello, Luigi [1 ,2 ,3 ]
机构
[1] Univ Messina, Dipartimento Sci Farmaco & Prod Salute SCIFAR, I-98168 Messina, Italy
[2] Univ Campus Biomed, CIR, Rome, Italy
[3] Chromaleont Srl, Messina, Italy
关键词
Coumarins; Flavonoids; Fused-core columns; Lime; Psoralens; PERFORMANCE LIQUID-CHROMATOGRAPHY; FLAVONOID COMPOSITION; BIOLOGICAL-ACTIVITY; BERGAMIA; IDENTIFICATION; EXTRACT;
D O I
10.1002/jssc.201300986
中图分类号
O65 [分析化学];
学科分类号
070302 [分析化学];
摘要
Reversed-phase-HPLC analysis by means of superficially porous silica particle columns (fused-core) was applied to the investigation of flavonoids, coumarins, and psoralens in lime juice samples. Hesperidin (367.0 +/- 16.0 ppm) and eriocitrin (148.0 +/- 7.9 ppm) were the most abundant flavonoids. Fifteen coumarins and furocoumarins were determined, including bergamottin (29.6 +/- 1.1 ppm), 5-geranyloxy-7-methoxycoumarin (16.5 +/- 0.6 ppm), and oxypeucedanin hydrate (9.9 +/- 0.5 ppm) as predominant compounds. These molecules are today well known for their beneficial effects on human health. As a consequence, the present study, beyond investigating for the first time the chemical composition of lime juice, highlights also its health-promoting qualities, due to its content of flavonoids and coumarins.
引用
收藏
页码:792 / 797
页数:6
相关论文
共 32 条
[1]
Recent trends in ultra-fast HPLC: New generation superficially porous silica columns [J].
Ali, Imran ;
Al-Othman, Zeid A. ;
Nagae, Norikaju ;
Gaitonde, Vinay D. ;
Dutta, Kamlesh K. .
JOURNAL OF SEPARATION SCIENCE, 2012, 35 (23) :3235-3249
[2]
[Anonymous], 1998, The fitness for purpose of analytical methods: A laboratory guide to method validation and related topics
[3]
Flavonoid profile and radical-scavenging activity of Mediterranean sweet lemon (Citrus limetta Risso) juice [J].
Barreca, Davide ;
Bellocco, Ersilia ;
Caristi, Corrado ;
Leuzzi, Ugo ;
Gattuso, Giuseppe .
FOOD CHEMISTRY, 2011, 129 (02) :417-422
[4]
Flavonoid Composition and Antioxidant Activity of Juices from Chinotto (Citrus x myrtifolia Raf.) Fruits at Different Ripening Stages [J].
Barreca, Davide ;
Bellocco, Ersilia ;
Caristi, Corrado ;
Leuzzi, Ugo ;
Gattuso, Giuseppe .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (05) :3031-3036
[5]
Simple coumarins and analogues in medicinal chemistry: Occurrence, synthesis and biological activity [J].
Borges, F ;
Roleira, F ;
Milhazes, N ;
Santana, L ;
Uriarte, E .
CURRENT MEDICINAL CHEMISTRY, 2005, 12 (08) :887-916
[6]
Determination of flavonoids in citrus juices by micro-HPLC-ESI/MS [J].
Dugo, P ;
Lo Presti, M ;
Öhman, M ;
Fazio, A ;
Dugo, G ;
Mondello, L .
JOURNAL OF SEPARATION SCIENCE, 2005, 28 (11) :1149-1156
[7]
Determination of Oxygen Heterocyclic Components in Citrus Products by HPLC with UV Detection [J].
Dugo, Paola ;
Piperno, Anna ;
Romeo, Roberto ;
Cambria, Maria ;
Russo, Marina ;
Carnovale, Caterina ;
Mondello, Luigi .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (15) :6543-6551
[8]
Gambari R, 2007, TOP HETEROCYCL CHEM, V9, P265, DOI 10.1007/7081_2007_089
[9]
Evaluation of flavonoids and furanocoumarins from Citrus bergamia (bergamot) juice and identification of new compounds [J].
Gardana, Claudio ;
Nalin, Federico ;
Simonetti, Paolo .
MOLECULES, 2008, 13 (09) :2220-2228
[10]
Flavonoid composition of citrus juices [J].
Gattuso, Giuseppe ;
Barreca, Davide ;
Gargiulli, Claudia ;
Leuzzi, Ugo ;
Caristi, Corrado .
MOLECULES, 2007, 12 (08) :1641-1673