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The medical utility of genomics data in neuropsychiatry: Mutational genetics versus association genetics

被引：5
作者：
Peroutka, SJ
机构：
[1] Spectra Biomedical, Inc., 111 Anza Boulevard, Bullingame
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 1997年 / 8卷 / 06期
关键词：
D O I：
10.1016/S0958-1669(97)80120-6
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The long anticipated 'genetic revolution' in neuropsychiatry has yet to have an impact on the practice or clinical medicine. Excitement in the 1980s over major genetic breakthroughs in schizophrenia and manic depression, for example, has been replaced in the late 1990s by the sobering realization that mast common neuropsychiatric disorders are multifactorial. Despite considerable effort and resources, no 'causative' genetic variation has been identified that plays a definitive major role in any common neuropsychiatric disorder. (C) Current Biology Ltd ISSN 0958-1669.
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页码：688 / 691
页数：4
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