α-Amidobenzylation of Aryl and Alkenyl Halides via Palladium-catalyzed Suzuki-Miyaura Coupling with α-(Acylamino)benzylboronic Esters

被引：27

作者：

Ohmura, Toshimichi ^{[1
]}

Awano, Tomotsugu ^{[1
]}

Suginome, Michinori ^{[1
]}

机构：

[1] Kyoto Univ, Dept Synthet Chem & Biol Chem, Grad Sch Engn, Nishikyo Ku, Kyoto 6158510, Japan

来源：

CHEMISTRY LETTERS | 2009年 / 38卷 / 07期

关键词：

ACID-DERIVATIVES; AMINOMETHYLATIONS; INHIBITION; ALDIMINES; CHLORIDES;

D O I：

10.1246/cl.2009.664

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Suzuki-Miyaura coupling of alpha-(acetylatnino)benzyl-boronic esters with aryl and alkenyl halides has been achieved using a Pd/P(t-Bu)(3) catalyst with KF and H2O in 1,4-dioxane, giving a-substituted benzylamines in high yields.

引用

页码：664 / 665

页数：2

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