Diagnostic Performance of the Cytomegalovirus (CMV) Antigenemia Assay in Patients with CMV Gastrointestinal Disease

被引：62

作者：

Jang, Eun-Young ^{[1
]}

Park, Seong Yeon ^{[1
]}

Lee, Eun Jung ^{[1
]}

Song, Eun Hee ^{[1
]}

Chong, Yong Pill ^{[1
]}

Lee, Sang-Oh ^{[1
]}

Choi, Sang-Ho ^{[1
]}

Woo, Jun Hee ^{[1
]}

Kim, Yang Soo ^{[1
]}

Kim, Sung-Han ^{[1
]}

机构：

[1] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Infect Dis, Seoul 138736, South Korea

来源：

CLINICAL INFECTIOUS DISEASES | 2009年 / 48卷 / 12期

关键词：

STEM-CELL TRANSPLANTATION; MARROW-TRANSPLANTATION; PREEMPTIVE THERAPY; RECIPIENTS; UTILITY;

D O I：

10.1086/599116

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable cases, and 64 (45%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of >= 1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54% (95% confidence interval, 41%-68%) and 88% (95% confidence interval, 77%-94%), respectively.

引用

页码：E121 / E124

页数：4

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